Von Willebrand disease

Term

Von Willebrand disease – one of the most common hemophilias, inherited in an autosomal dominant manner. Clinically manifests as subcutaneous hematoma, bleeding from mucous membranes, menorrhagia. Von Willebrand disease has 3 types. This disease is caused by a deficiency of factor VIII in blood coagulation, which, together with factor IX, phospholipids, and calcium, is necessary to activate factor X. Platelet adhesion is impaired. The disease is characterized by prolonged bleeding time.

Source | Glossary of Most Commonly Used Biomedical Terms and Concepts | Lithuanian University of Health Sciences | Academician Professor Antanas Praškevičius, Professor Laima Ivanovienė