ANCA (Antineutrophilic Cytoplasmic Antibodies)

Norma
Not found

Synonyms: c-ANCA, p-ANCA, proteinase 3, PR 3, antibodies to neutrophil cytoplasmic antigens.
Serum
Red cap

This indicator helps diagnose Wegener’s granulomatosis and allows differentiation between primary biliary cirrhosis and sclerosing cholangitis. This indicator is also useful in differentiating ulcerative colitis. The investigation of Wegener’s granulomatosis involves identifying a specific triad: granulomatous inflammation of the respiratory tract, vasculitis, and glomerulonephritis. The ANCA test result can be presented in three possible variants: 1) negative reaction; 2) cytoplasmic type reaction – c-ANCA; 3) perinuclear type reaction – p-ANCA.

Source | Handbook of Basic Laboratory Tests | Doctor of Medical Sciences Gintaras Zaleskis